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Home PageAll Molecules218 linker
218 linker
218 linker Product List
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Antibody (6)
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Launched (6)
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Rabbit (6)
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- (6)
- Conjugate
APC Labeled (1)PE Labeled (1)AF488 Labeled (1)Unconjugated (2)AF647 Labeled (1)
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Total: 6
- 1
218 linker Background
The whitlow/218 linker, with the sequence GSTSGSGKPGSGEGSTKG, is a commonly used synthetic peptide linker. Whitlow/218 linker often leveraged to connect the variable heavy (VH) domain and variable light (VL) domain of single-chain variable fragments (scFvs) and chimeric antigen receptors (CARs) that utilize an extracellular domain scFv for target antigen recognition. The scFv containing the 218 linker showed reduced aggregation and was found to be more stable to proteolysis in vitro.
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