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Menu
Home PageAll MoleculesCadherin-17
Cadherin-17
Cadherin-17 Overview
| English Name | Cadherin-17 | Approved Drugs | 0 |
| Drugs in Clinical Trials | 8 | Target Synonym | Liver-intestine cadherin，HPT-1，Intestinal peptide-associated transporter HPT-1，LI-cadherin，HPT-1 Cadherin，Cadherin 17， LI Cadherin (Liver-Intestine)，HPT1，Human Intestinal Peptide-Associated Transporter HPT-1，LI Cadherin，Cadherin，Cadherin 17，Human Peptide Transporter 1 |
| Highest Development Stage | Phase 2 Clinical | ||
| English Name | Cadherin-17 |
| Target Synonym | Liver-intestine cadherin，HPT-1，Intestinal peptide-associated transporter HPT-1，LI-cadherin，HPT-1 Cadherin，Cadherin 17， LI Cadherin (Liver-Intestine)，HPT1，Human Intestinal Peptide-Associated Transporter HPT-1，LI Cadherin，Cadherin，Cadherin 17，Human Peptide Transporter 1 |
| Approved Drugs | 0 |
| Drugs in Clinical Trials | 8 |
| Highest Development Stage | Phase 2 Clinical |
Cadherin-17 Product List
- Product Category
Protein (29)Cell (1)
- Product Status
Launched (31)
- Species
Mouse (4)Human (22)Rat (1)Cynomolgus (3)
- Tag
His Tag (10)His Tag & Avi Tag (4)Mouse IgG Fc Tag (1)Fc Tag (12)Fc Tag & Avi Tag (2)- (2)
- Conjugate
Unconjugated (22)Biotin-labeled (6)- (2)FITC Labeled (1)
Add to Cart
Total: 30
- 1
- 2
- 3
Cadherin-17 Background
Cadherin-17, also known as liver-intestine (LI) Cadherin, belongs to the cadherin family of calcium-dependent cell adhesion molecules. In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
Cadherin-17 Synonyms
Cadherin-17,CDH17,HPT-1,LI-cadherin
Antibody Project Trading Platform
| Project Name | Project Stage | Molecule Type | Molecule Source | Disease Area | Indication |
|---|---|---|---|---|---|
| CDH17 mAb - 01 | PCC | Monoclonal | Humanized Mouse | Solid Tumor | Colorectal cancer,Gastric Cancer |
Clinical Drug Information
| English Name | Research Code | Highest Development Stage | Company | Indication | Clinical Trial |
|---|---|---|---|---|---|
| CHM-2101 | CDH17-CAR T; CHM-2101; CHM2101; CHM-2101 CAR-T cells | Phase 2 Clinical | University Of Pennsylvania | Stomach Neoplasms; Pancreatic Neoplasms; Neuroendocrine Tumors; Colorectal Neoplasms; Gastrointestinal Neoplasms | Details |
| BI-905711 | BI-905711 | Phase 1 Clinical | Boehringer Ingelheim Gmbh | Pancreatic Neoplasms; Cholangiocarcinoma; Gastrointestinal Neoplasms | Details |
| Cabotamig | ARB-202 | Phase 1 Clinical | Arbele Corp | Liver Neoplasms; Biliary Tract Neoplasms; Stomach Neoplasms; Pancreatic Neoplasms; Cholangiocarcinoma; Colorectal Neoplasms; Esophageal adenocarcinoma; Gastrointestinal Neoplasms | Details |
| Anti-CDH17 CAR-T cells Therapy (Guangzhou Bio-Gene Technology) | Phase 1 Clinical | Guangzhou Bio-Gene Technology Co Ltd | Solid tumours | Details | |
| HS-20110 | HS20110; HS-20110 | Phase 1 Clinical | Shanghai Hansoh Biomedical Co Ltd, Changzhou Hengbang Pharmaceutical Co Ltd | Solid tumours | Details |
| Anti-CDH17 CAR-T Cell therapy (UTC Therapeutics) | Phase 1 Clinical | UTC Therapeutics Inc | Solid tumours | Details | |
| TORL-3-600 | TORL-3-600 | Phase 1 Clinical | Torl Biotherapeutics LLC | Solid tumours; Colorectal Neoplasms | Details |
| CDH17 - IHC Test(Arbele) | Clinical | Arbele Corp | Gastrointestinal Neoplasms | Details |
Product Reviews
T***I2025-11-07
0People LikeThis time purchased 100ug human protein FG9-H51H3, used for validation experiments. The experimental bands are clear, antigen-antibody binding effect is good, overall experience is good, will repurchase.
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