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Menu
Home PageAll MoleculesCadherin-6
Cadherin-6
Cadherin-6 Overview
| English Name | Cadherin-6 | Approved Drugs | 0 |
| Drugs in Clinical Trials | 4 | Target Synonym | Kidney cadherin，K-cadherin，Cadherin 6， Type 2， K-Cadherin (Fetal Kidney)，K-Cadherin，Cadherin-6，Kidney Cadherin，CAD6，KCAD |
| Highest Development Stage | Phase 3 Clinical | ||
| English Name | Cadherin-6 |
| Target Synonym | Kidney cadherin，K-cadherin，Cadherin 6， Type 2， K-Cadherin (Fetal Kidney)，K-Cadherin，Cadherin-6，Kidney Cadherin，CAD6，KCAD |
| Approved Drugs | 0 |
| Drugs in Clinical Trials | 4 |
| Highest Development Stage | Phase 3 Clinical |
Cadherin-6 Product List
- Product Category
Protein (6)Cell (1)
- Product Status
Launched (8)
- Species
Human (4)Cynomolgus / Rhesus macaque (1)Mouse (1)Rat (1)
- Tag
His Tag (4)Fc Tag (1)His Tag & Avi Tag (1)- (2)
- Conjugate
Unconjugated (5)Biotin-labeled (1)- (2)
| Cat. No. | Species | Host | Product Description | Structure | Purity | Feature | Order Now |
|---|---|---|---|---|---|---|---|
HOT CA6-H5229 |  Human | HEK293 | Human Cadherin-6 / KCAD / CDH6 Protein, His Tag, low endotoxin (HPLC verified) |  |  |  |  Add to Cart |
HOT CA6-H5258 | Human | HEK293 | Human Cadherin-6 / KCAD / CDH6 Protein, Fc Tag (MALS verified) |  | | | Add to Cart |
HOT CA6-H82E3 | Human | HEK293 | Biotinylated Human Cadherin-6 / KCAD / CDH6 Protein, His,Avitag™ (MALS verified) |  | | | Add to Cart |
HOT CA6-C52H3 |  Cynomolgus / Rhesus macaque | HEK293 | Cynomolgus / Rhesus macaque Cadherin-6 / KCAD / CDH6 Protein, His Tag, low endotoxin |  | | | Add to Cart |
CHEK-ATP127 | Human | HEK293 | HEK293/Human Cadherin-6 Stable Cell Line |  | Add to Cart | ||
CA6-M52H8 |  Mouse | HEK293 | Mouse Cadherin-6 / KCAD / CDH6 Protein, His Tag |  | | | Add to Cart |
CA6-R52H3 |  Rat | HEK293 | Rat Cadherin-6 / KCAD / CDH6 Protein, His Tag (MALS verified) |  | | | Add to Cart |
Total: 7
- 1
Cadherin-6 Background
Cadherin-6 (CDH6) is also known as Kidney cadherin (K-cadherin or KCAD), is a a type II classical cadherin from the cadherin superfamily. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH6 / KCAD contains five cadherin domains. CDH6 is highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression and also expressed in certain liver and kidney carcinomas.
Cadherin-6 Synonyms
CDH6,CAD6,KCAD,K-cadherin,Cadherin-6
Antibody Project Trading Platform
| Project Name | Project Stage | Molecule Type | Molecule Source | Disease Area | Indication |
|---|---|---|---|---|---|
| CDH6 mAb - 01 | PCC | Monoclonal | Humanized Mouse | Solid Tumor | Ovarian cancer,Renal cell carcinoma |
Clinical Drug Information
| English Name | Research Code | Highest Development Stage | Company | Indication | Clinical Trial |
|---|---|---|---|---|---|
| Raludotatug deruxtecan | DS-6000a; DS6000a; DS-6000; R-DXd; MK-5909 | Phase 3 Clinical | Daiichi Sankyo Co Ltd | Ovarian Neoplasms; Solid tumours; Carcinoma, Renal Cell; Peritoneal Neoplasms; Fallopian Tube Neoplasms; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Gastrointestinal Neoplasms | Details |
| HS-20124 | HS-20124; HS20124 | Phase 1 Clinical | Hansoh BioMedical R&D Company | Solid tumours | Details |
| SIM-0505 | SIM-0505 | Phase 1 Clinical | Hainan Xiansheng Re Ming Pharmaceutical Co Ltd | Solid tumours | Details |
| AMT-707 | AMT-707; CUSP-06 | Phase 1 Clinical | Multitude Therapeutics Inc | Solid tumours; Ovarian Neoplasms; Carcinoma, Renal Cell; Cholangiocarcinoma | Details |
Product Reviews
1***62022-08-09
1People LikeValidated by SPR, measured monovalent affinity, anti-human FC chip, load diluted antibody, added diluted CDH6, His tag, with the affinity constant of 4.72 nM.
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