CD23

CD23

CD23 Overview

Molecule Name
Immunoglobulin epsilon Fc receptor
Synonyms
FCER2,CD23,CD23A,CLEC4J,FCE2,IGEBF,FcεRII,FcεRⅡ
Drug Development Progress
Drugs in Clinical Trials2
Approved Drugs0
Highest Development StagePhase 2 Clinical
Target Synonym
Low affinity immunoglobulin epsilon Fc receptor,FCE2,CD23A,FCER2,CLEC4J,BLAST-2,Fc Fragment Of IgE Receptor II,C-Type Lectin Domain Family 4, Member J,Immunoglobulin Epsilon-Chain,CD23,Lymphocyte IgE Receptor,Fc Epsilon Receptor II,Fc-Epsilon-RII,CD23 Antigen,IGEBF,Fc Fragment Of IgE, Low Affinity II, Receptor For (CD23A),C-Type Lectin Domain Family 4 Member J,Immunoglobulin E-binding factor,Fc Fragment Of IgE, Low Affinity II, Receptor For (CD23)
Background
Cluster of differentiation 23 (CD23) is also known as Low affinity immunoglobulin epsilon Fc receptor (FCER2), C-type lectin domain family 4 member J (CLEC4J), Fc-epsilon-RII (FcεRII), Immunoglobulin E-binding factor (IGEBF), is the 'low-affinity' receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, and is important in regulation of IgE levels. Unlike many of the antibody receptors, CD23 is a C-type lectin. It is found on mature B cells, activated macrophages, eosinophils, follicular dendritic cells, and platelets.

CD23 Product List

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Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
UB-221UB-221Phase 2 ClinicalChinese Academy Of Sciences
Chronic Urticaria
Details
RO-7297089RO-7297089; AFM-26; RG-6296Phase 1 ClinicalGenentech Inc
Multiple Myeloma
Details