Serpin G1

Serpin G1 Overview

English NamePlasma protease C1 inhibitorApproved Drugs0
Drugs in Clinical Trials1Target SynonymC1 Inh,C1Inh,C1 esterase inhibitor,C1-inhibiting factor,Serpin G1,Serpin Family G Member 1
Highest Development StagePhase 2 Clinical
English NamePlasma protease C1 inhibitor
Target SynonymC1 Inh,C1Inh,C1 esterase inhibitor,C1-inhibiting factor,Serpin G1,Serpin Family G Member 1
Approved Drugs0
Drugs in Clinical Trials1
Highest Development StagePhase 2 Clinical

Serpin G1 Product List

  • Product Category

    Protein (1)

  • Product Status

    Launched (1)

  • Species

    Human (1)

  • Tag

    His Tag (1)

  • Conjugate

    Unconjugated (1)

Cat. No.SpeciesHostProduct DescriptionStructurePurityFeature
SER-H52H5
Human
HEK293
Human Serpin G1 / C1 inhibitor Protein, His Tag (active enzyme, MALS verified)
Total: 1
  • 1

Serpin G1 Background

Serpin G1/C1-inhibitor (C1-INH) is an important regulator of the complement, coagulation, fibrinolytic and contact systems. The quantity of protease/C1-INH complexes in the blood is proportional to the level of the in vivo activation of these four cascade-like plasma enzyme systems. It inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. It is synthesized in the liver, and its deficiency is associated with hereditary angioneurotic oedema (HANE).

Serpin G1 Synonyms

SERPING1,C1IN,C1-INH,C1IN,HAE1,HAE2

Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
BMN-331BMN 331; BMN-331Phase 2 ClinicalBiomarin Pharmaceutical IncAngioedemas, Hereditary
Details
  • Product List
  • Clinical Drug Information
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