user
cart
menu
orderQuote Inquiry / OrdercartCart
letter
Sign InRegister
langEnglisharrow

APC-CY7-Labeled Monoclonal Anti-Human CD8 Antibody, Mouse IgG1

Cat. No. / Size
Price
Availability
Qty
FABm003-05-50tests
$180.00
In Stock - Delivery in 2-3 weeks
FABm003-05-200tests (50tests X 4)
$560.00
In Stock - Delivery in 2-3 business days
FABm003-05
Sub-Total :
$ 0
0
Add to Cart
Customize Product Request Quote
Contact Us
Contact Us
Sub-Total:
$ 0
0
Add to Cart
Request Quote
Product Details
Performance Data
Reviews & Citations
Resources
Add to Cart
  • Product Details
  • Performance Data
  • Reviews & Citations
  • Important Statement
  • Resources
Clone

AS228

Isotype

Mouse IgG1, Kappa

Host Species

Mouse

Reactivity

Human

Conjugate

APC-CY7

Excitation Wavelength: 637 nm

Emission Wavelength: 780 nm

Specificity

This product is a specific antibody specifically reacts with CD8 protein.

Application

This APC-CY7-CD8 Antibody is specifically developed for flow cytometry applications to detect the expression of CD8 on human cells. Additionally, the Human TBNK 6-color Cocktail Flow Panel kit (Cat. No. ICA-A001) is available, with the APC-CY7-CD8 Antibody being one component of the kit.

Recommended Dilution

1:20

Form

Liquid

Formulation

Supplied as 0.2 μm-filtered solution in PBS (pH 7.4) containing 0.03% ProClin 300 and 0.2% BSA, with trehalose as protectant.

Please contact us for customized product forms or formulations.

Shipping

Liquid product is shipped at blue ice.

Storage

Please protect from light and avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • Store at 2-8 °C for 12 months.
Notices

Product Specific Notices: For research use only.

ACRO Quality Management System

Background

CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.