Monoclonal Anti-Rabies virus (strain CVS-11) Nucleoprotein Antibody, Mouse IgG2b (2A12)

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NUN-MY2302-100ug
$399.00
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NUN-MY2302-1mg (500ug X 2)
$2,625.00
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NUN-MY2302
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Source

Chimeric Monoclonal Anti-Rabies virus (strain CVS-11) Nucleoprotein Antibody, Mouse IgG2b (2A12) is recombinantly expressed in HEK293. It consists of mouse variable regions genetically fused to mouse IgG2b constant domains.

Antibody Type

Recombinant Monoclonal

Clone

2A12

Isotype

Mouse IgG2b, Kappa

Host Species

Mouse

Reactivity

Virus

Immunogen

Recombinant Rabies virus (strain CVS-11) Nucleoprotein is expressed from Baculovirus-Insect cells

Specificity

Specifically recognizes Rabies virus (strain CVS-11) Nucleoprotein.

Application
Application
Recommended Use / Performance
ELISA
0.2-2 μg/mL
Purification

Protein A purified.

Aggregation

Less than 10%, as determined by SEC-MALS.

Concentration

Please refer to the Certificate of Analysis (CoA).

Form

Lyophilized

Formulation

Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

Please contact us for customized product forms or formulations.

Reconstitution

Please refer to the Certificate of Analysis (CoA) for specific instructions.

Shipping

Lyophilized product is shipped at ambient temperature.

Storage

For long term storage, the product should be stored in a lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • -20°C to -70°C for 12 months in lyophilized state;
  • -70°C for 3 months under sterile conditions after reconstitution.
Notices

Product Specific Notices: For research use only.

Background

The ​​Anti-Rabies Virus Nucleoprotein Antibody​​ targets the ​​nucleoprotein (N protein)​​ of rabies virus (RABV), a structural protein essential for viral replication. The N protein encapsidates the viral RNA genome, forming the ribonucleoprotein (RNP) complex that serves as the template for transcription and replication by the viral polymerase. This antibody is typically generated using recombinant N protein as an immunogen and purified via affinity chromatography. It is widely used for ​​detecting rabies virus in diagnostic assays​​ such as immunofluorescence, Western blotting, and ELISA, aiding in the identification of viral inclusions like Negri bodies in infected neural tissues. Its specificity supports research on viral pathogenesis and host immune responses.