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Monoclonal Anti-HRSV F-hRSV90 Antibody, Human IgG1

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HRV-M720-100ug
$415.00
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HRV-M720-1mg
$2,735.00
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HRV-M720
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  • Product Details
  • Performance Data
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  • Important Statement
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Source

Chimeric Monoclonal Anti-HRSV F-hRSV90 Antibody, Human IgG1 is recombinantly expressed in HEK293. It consists of mouse variable regions genetically fused to human IgG1 constant domains.

Antibody Type

Recombinant Monoclonal

Clone

hRSV90

Isotype

Human IgG1, Kappa

Host Species

Mouse

Reactivity

Virus

Specificity

This product is a specific antibody specifically reacts with HRSV F.

Application
Application
Recommended Use / Performance
ELISA
0.2-2 μg/mL
Purification

Protein A purified.

Aggregation

Less than 5%, as determined by SEC-MALS.

Concentration

Please refer to the Certificate of Analysis (CoA).

Form

Liquid

Formulation

Supplied a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

Please contact us for customized product forms or formulations.

Storage

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • The product MUST be stored at -70°C or lower upon receipt;
  • -70°C for 12 months under sterile conditions.
Notices

Product Specific Notices: For research use only.

ACRO Quality Management System

Background

Human respiratory syncytial virus (HRSV) is the most common etiological agent of acute lower respiratory tract disease in infants and can cause repeated infections throughout life. The RSV fusion glycoprotein (RSV F) is the principal target of RSV neutralizing antibodies in human sera. The RSV F is a type I viral fusion protein synthesized as inactive, single‑chain polypeptides that assemble into trimers. RSV F fuses the viral and host cell membranes by irreversible protein refolding from the labile prefusion conformation to the stable post‑fusion conformation. The antibody hRSV90 recognizes a prefusion‑specific epitope encompassing residues 163–181 within antigenic site V on the RSV F protein.