SPR /BLI analytical service
Biomolecular interaction analysis is used increasingly in drug development to kinetically characterize binding events of relevant components, including drugs and targets, antibodies and antigens or any pair of interacting molecules. Based on the Biacore 8K and ForteBio Octet platforms, ACROBiosystems provides biopharmaceutical R&D customers with complementary molecular interaction analysis services, including antibody screening, characterization, consistency evaluation, and biomolecule interactions that contribute to therapeutics development.
Promotion
ACRO proteins supplied free
（Multi-pass transmembrane proteins are excluded, as well as FcR and MHC proteins when they are used as analytes）
Only provide samples to get service completed
All Fc receptor proteins needed are free of charge
（Except when FcR is used as the analyte）
Only provide analytes, then get the full service
Case study
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Anti- BCMA antibodies (Mouse IgG1) captured on CM5 chip via anti-Mouse IgG antibodies, can bind to Human BCMA Protein, His Tag (Cat. No. BCA-H522y) as determined using a SPR (Biacore T200).
Bispecific T-cell Engager (CD3×BCMA) immobilized on CM5 Chip can bind Human CD3E&CD3D Heterodimer Protein, His Tag&Tag Free (Cat. No. CDD-H52W1) with an affinity constant of 31.8 nM as determined in a SPR assay (Biacore T200).
Bispecific T-cell Engager (CD3×BCMA) immobilized on CM5 Chip can bind Human CD3E&CD3D Heterodimer Protein, His Tag&Tag Free (Cat. No. CDD-H52W1) with an affinity constant of 31.8 nM as determined in a SPR assay (Biacore T200).
Batch consistency of Human Fc gamma RIIB / CD32b (Cat. No. CDB-H5228). The similarity of Human Fc gamma RIIB / CD32b (Cat. No. CDB-H5228) for different batches is more than 90% (Biacore T200).
Bispecific antibody (BsAb-IgG)binding with Fc gamma Receptor
The affinity between different IgG antibody subtypes and Human FcRn Protein (Cat. No.FCM-H82W4)
IL-15 (Cat. No. IL5-H52H8) binding with IL-2 R beta with an affinity constant of 0.21 nM as determined in a SPR assay(Biacore T200).
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SARS-CoV-2 3CL-Mpro, His Tag immobilized on CM5 Chip can bind to Dipγridamole with an affinity constant of 65.1 μM as determined in a SPR assay (Biacore T200) (Routinely tested).
Service Advantages
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● Worry-Free Service: Comprehensive high-quality Fc proteins needed are free of charge, only your samples required
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● Data Quality Meets Filing Requirements: Customized solution designs and report formats from our professional technical team
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● Rapid Response: Next-day reports at the earliest with our mature project operations team, 1-on-1 service follow-up and feedback throughout the project
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● High-standard Quality Management System: Platforms based on the standards of the USP and ChP with IS09001/ISO13485/ISO17025 Quality Certification
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● Multiple Service Locations: Newark, U.S. & Beijing, China
Certification
In December 2024，ACROBiosystems’ US Innovation Lab has achieved ISO/IEC 17025 accreditation for Surface Plasmon Resonance (SPR) analytical service, ensuring that results from this service is globally recognized and trusted for its precision and consistency.
- Platforms
- Promotion
- Case study
- Service Advantages
- Certification