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CD47

CD47信息

英文名称:Cluster of differentiation 47上市药物数量0
中文名称分化群47临床药物数量51
靶点别称MER6，CD47，Leukocyte surface antigen CD47，CD47 Molecule，Antigenic Surface Determinant Protein OA3，CD47 Antigen (Rh-Related Antigen， Integrin-Associated Signal Transducer)，Antigen Identified By Monoclonal Antibody 1D8，Integrin Associated Protein，Rh-Related Antigen，CD47 Glycoprotein，IAP，Integrin-Associated Signal Transducer，Protein MER6，OA3，CD47 Antigen，Integrin-Associated Protein最高研发阶段Phase 2 Clinical
英文名称:Cluster of differentiation 47
中文名称分化群47
靶点别称MER6，CD47，Leukocyte surface antigen CD47，CD47 Molecule，Antigenic Surface Determinant Protein OA3，CD47 Antigen (Rh-Related Antigen， Integrin-Associated Signal Transducer)，Antigen Identified By Monoclonal Antibody 1D8，Integrin Associated Protein，Rh-Related Antigen，CD47 Glycoprotein，IAP，Integrin-Associated Signal Transducer，Protein MER6，OA3，CD47 Antigen，Integrin-Associated Protein
上市药物数量0
临床药物数量51
最高研发阶段Phase 2 Clinical

CD47产品列表

  • 属性

    Protein (22)Beads (3)Kits (3)

  • 产品库

    在线 (27)在研 (2)

  • 物种

    Human (16)Cynomolgus / Rhesus macaque (4)Mouse (5)Rat (1)Rabbit (1)Canine (1)

  • 标签

    Fc Tag & Avi Tag (3)Fc Tag (5)His Tag (7)Mouse IgG Fc Tag (2)His Tag & Avi Tag (5)Llama IgG Fc Tag (1)Mouse IgG Fc Tag & Avi Tag (1)- (5)

  • 标记

    Biotin-labeled (7)Unconjugated (14)FITC Labeled (1) (4)PE Labeled (1)APC Labeled (1)

共 28 项数据
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CD47分子背景

Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation.

CD47分子别名

CD47,MER6,IAP,OA3

Licensing 项目合作

产品评论

  • 25********qq.com 2024-10-22
    0人点赞
    Human CD47 Protein, His Tag (MALS verified)
    在CD47靶点单克隆抗体研发项目中用到该抗原重组蛋白，蛋白活力很高，通过低浓度铺板筛到了多个高亲和力突变抗体，后期BLI检测Kd数据也很理想。
  • 25********qq.com 2024-09-30
    0人点赞
    Human CD47 Protein, His Tag (MALS verified)
    之所以选择该货号CD47重组蛋白，主要是因为活性稳定，带有his tag很适合抗体淘筛及Elisa亲和力检测，拿到的数据非常不错，推荐购买试用！
  • ga*******126.com 2024-09-18
    0人点赞
    Human CD47 Protein, His Tag (MALS verified)
    购买Human CD47 Protein主要用于动物免疫，蛋白不仅活性高，而且毒副作用小，免疫后的动物状态都很不错，四免获得的血清效价也很nice，物有所值。
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