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EpCAM

EpCAM信息

英文名称:Epithelial cell adhesion molecule上市药物数量1
中文名称上皮细胞粘附分子临床药物数量10
靶点别称Epithelial Cell Adhesion Molecule，Tumor-Associated Calcium Signal Transducer 1，Major Gastrointestinal Tumor-Associated Protein GA733-2，Cell Surface Glycoprotein Trop-1，Epithelial Glycoprotein 314，TROP1，KSA，Membrane Component， Chromosome 4， Surface Marker (35kD Glycoprotein)，Antigen Identified By Monoclonal Antibody AUA1，Human Epithelial Glycoprotein-2，Epithelial Cell Surface Antigen，CD326 Antigen，HEGP314，HNPCC8，Ep-CAM，DIAR5，EGP-2，EGP40，KS1/4，MK-1，M1S2，ESA，Ly74，TACST-1，CO-17A，17-1A，EGP34，HEA125，MH99，MOC31，323/A3，Trophoblast Cell Surface Antigen 1，Adenocarcinoma-associated antigen，EGP314，GA733-2，M4S1，TACSTD1，Epithelial glycoprotein，EGP，KS 1/4 antigen，MIC18，CD326，EPCAM最高研发阶段Approved
英文名称:Epithelial cell adhesion molecule
中文名称上皮细胞粘附分子
靶点别称Epithelial Cell Adhesion Molecule，Tumor-Associated Calcium Signal Transducer 1，Major Gastrointestinal Tumor-Associated Protein GA733-2，Cell Surface Glycoprotein Trop-1，Epithelial Glycoprotein 314，TROP1，KSA，Membrane Component， Chromosome 4， Surface Marker (35kD Glycoprotein)，Antigen Identified By Monoclonal Antibody AUA1，Human Epithelial Glycoprotein-2，Epithelial Cell Surface Antigen，CD326 Antigen，HEGP314，HNPCC8，Ep-CAM，DIAR5，EGP-2，EGP40，KS1/4，MK-1，M1S2，ESA，Ly74，TACST-1，CO-17A，17-1A，EGP34，HEA125，MH99，MOC31，323/A3，Trophoblast Cell Surface Antigen 1，Adenocarcinoma-associated antigen，EGP314，GA733-2，M4S1，TACSTD1，Epithelial glycoprotein，EGP，KS 1/4 antigen，MIC18，CD326，EPCAM
上市药物数量1
临床药物数量10
最高研发阶段Approved

EpCAM产品列表

  • 属性

    Protein (11)Antibody (1)Cell (1)

  • 产品库

    在线 (15)

  • 物种

    Human (9)Mouse (1)Rhesus macaque (2)Rabbit (1)

  • 标签

    His Tag (4)Fc Tag (2)His Tag & Avi Tag (2)Fc Tag & Avi Tag (1)Mouse IgG Fc Tag (1)Llama IgG Fc Tag (1)- (4)

  • 标记

    Unconjugated (7)Biotin-labeled (3)FITC Labeled (2) (1)

共 13 项数据
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EpCAM分子背景

EpCAM is also known as CO171A, EGP, EGP40,GA7332, KSA, M4S, MIC18, MK1, TROP1, hEGP2, and is a pan-epithelial differentiation antigen that is expressed on almost all carcinomas as 17-1A(mAb) antigen. Its constitutional function is being elucidated. It is intricately linked with the Cadherin-Catenin pathway and hence the fundamental WNT pathway responsible for intracellular signaling and polarity. The epithelial cell adhesion molecule (Ep-CAM) is known to express in most epithelial malignancies and was reported as a tumor marker or a candidate of molecular targeting therapy. Ep-CAM cross signaling with N-cadherin involves Pi3K, resulting in the abrogation of the cadherin adhesion complexes in epithelial cells was reported. And Epithelial cell adhesion molecule (Ep-CAM) recently received increased attention as a prognostic factor in breast cancer.

EpCAM分子别名

EPCAM,TACSTD1,TROP1,CD326,DIAR5,EGP2,EGP314,EGP40,ESA,GA733-2,HNPCC8,HNPCC-8,KS1,4,KSA,M4S1,MIC18,MK1

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产品评论

  • 25********qq.com 2025-03-19
    0人点赞
    Human EpCAM / TROP1 Protein, His Tag
    本次采购Human EpCAM重组蛋白用于目标抗体亲和力检测，采用BLI的方法进行测定，蛋白活性稳定，经过泛素化处理后很容易固化到芯片上，检测起来很方便，数据特异性也非常不错。
  • 25********qq.com 2025-03-17
    0人点赞
    Human EpCAM / TROP1 Protein, His Tag
    购买该货号抗原重组蛋白，其主要用途为纳米抗体筛选。在初步的质量控制（QC）检测环节，我用市售阳性抗体进行测试，所得结果与产品说明书所述高度吻合，完全满足我们利用噬菌体展示抗体库进行筛选时对蛋白的标准要求。目前，我们筛选已富集成功，在后续的抗体活性及功能检测工作中，还会回购该蛋白。
  • 22********qq.com 2024-12-30
    0人点赞
    Human EpCAM / TROP1 Protein, His Tag
    合作方前期提供了该货号重组蛋白进行纳米抗体筛选，效果很不错，本次回购用于抗体亲和力检测，该批次蛋白活性依然很不错，价格亲民，值得推荐。
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  • 分子信息
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