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GITR

GITR信息

英文名称:Glucocorticoid-induced tumor necrosis factor receptor-related protein上市药物数量0
中文名称糖皮质激素诱导的肿瘤坏死因子受体相关蛋白临床药物数量4
靶点别称TNFRSF18，TNF Receptor Superfamily Activation-Inducible Protein，ENERGEN，GITR-D，Tumor Necrosis Factor Receptor Superfamily Member 18，CD357 Antigen，Activation-Inducible TNFR Family Receptor，AITR，CD357，GITR，Glucocorticoid-Induced TNFR-Related Protein，Tumor Necrosis Factor Receptor Superfamily， Member 18，TNF Receptor Superfamily Member 18最高研发阶段Phase 2 Clinical
英文名称:Glucocorticoid-induced tumor necrosis factor receptor-related protein
中文名称糖皮质激素诱导的肿瘤坏死因子受体相关蛋白
靶点别称TNFRSF18，TNF Receptor Superfamily Activation-Inducible Protein，ENERGEN，GITR-D，Tumor Necrosis Factor Receptor Superfamily Member 18，CD357 Antigen，Activation-Inducible TNFR Family Receptor，AITR，CD357，GITR，Glucocorticoid-Induced TNFR-Related Protein，Tumor Necrosis Factor Receptor Superfamily， Member 18，TNF Receptor Superfamily Member 18
上市药物数量0
临床药物数量4
最高研发阶段Phase 2 Clinical

GITR产品列表

  • 属性

    Protein (9)

  • 产品库

    在线 (9)

  • 物种

    Human (5)Rat (1)Rhesus macaque (1)Canine (1)Mouse (1)

  • 标签

    His Tag (4)Fc Tag (2)Mouse IgG Fc Tag (1)Fc Tag & Avi Tag (1)His Tag & Avi Tag (1)

  • 标记

    Unconjugated (7)Biotin-labeled (2)

共 9 项数据
  • 1

GITR分子背景

Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.

GITR分子别名

AITR,GITR,TNFRSF18,CD357

产品评论

  • Ca****** 2023-03-09
    0人点赞
    Human GITR / TNFRSF18 Protein, His Tag (MALS verified)
    购买该产品主要用于小鼠免疫和体外功能实验。在小鼠免疫方面，二免时使用猴GITR蛋白，流式检测效价时小鼠血清与猴GITR有比较好的结合，能达到10万效价。体外实验主要是进行抗体的亲和力筛选，蛋白活性很好，抗体分子与该蛋白有比较好的结合/解离曲线。后续会一直使用此款产品。
  • 2019-09-27
    4人点赞
    Human GITR / TNFRSF18 Protein, His Tag (MALS verified)
    使用Acro的产品很久了，不管是产品还是技术，每次都是有问题及时解决。用过的GITR蛋白，做过SPR实验，6个浓度梯度做，拟合曲线也很不错，数据也是达到我的预期，希望以后还是合作愉快。
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