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IL-2 R alpha

IL-2 R alpha信息

英文名称:Interleukin-2 receptor alpha chain上市药物数量3
中文名称白细胞介素-2受体α链临床药物数量16
靶点别称TAC antigen，p55，IL2-RA，Interleukin-2 receptor subunit alpha，IL-2-RA，IL-2R subunit alpha，IL2RA，Interleukin 2 Receptor Subunit Alpha，Interleukin 2 Receptor， Alpha，IL-2 Receptor Subunit Alpha，Insulin-Dependent Diabetes Mellitus 10，CD25 Antigen，IDDM10，IMD41，TCGFR，CD25，Interleukin-2 Receptor alpha Subunit，IL-2R alpha最高研发阶段Approved
英文名称:Interleukin-2 receptor alpha chain
中文名称白细胞介素-2受体α链
靶点别称TAC antigen，p55，IL2-RA，Interleukin-2 receptor subunit alpha，IL-2-RA，IL-2R subunit alpha，IL2RA，Interleukin 2 Receptor Subunit Alpha，Interleukin 2 Receptor， Alpha，IL-2 Receptor Subunit Alpha，Insulin-Dependent Diabetes Mellitus 10，CD25 Antigen，IDDM10，IMD41，TCGFR，CD25，Interleukin-2 Receptor alpha Subunit，IL-2R alpha
上市药物数量3
临床药物数量16
最高研发阶段Approved

IL-2 R alpha产品列表

  • 属性

    Protein (7)

  • 产品库

    在线 (8)

  • 物种

    Human (4)Mouse (1)Canine (1)Cynomolgus (1)

  • 标签

    His Tag (4)Fc Tag (1)His Tag & Avi Tag (1)Fc Tag & Avi Tag (1)

  • 标记

    Unconjugated (5)Biotin-labeled (2)

共 7 项数据
  • 1

IL-2 R alpha分子背景

Interleukin-2 receptor subunit alpha (IL2RA) is also known as IL-2R subunit alpha, IL-2-RA, IL2-RA, TAC antigen, p55, CD antigen CD25, is a type I transmembrane glycoprotein. IL2RA is expressed on activated T cells and regulatory T cells, and is capable of binding IL2 with low affinity by itself. However, a ligand-induced high affinity heterotrimeric receptor complex is produced when IL2RA is associated non-covelently with the IL2 receptor beta and gamma chain, and subsequently initiates the intacellular signal pathways such as MAPK or JAK/STAT. On dendritic cells (DC), CD25 has been previously regarded as an activation marker, while both murine and human DC can express CD25, they do not express the beta-chain of the IL-2 receptor, which is indispensable for the execution of IL-2 signaling.

IL-2 R alpha分子别名

IL2RA,CD25,p55,IL2-RA,IL-2-RA

抗体项目交易平台

产品评论

  • 15********qq.com 2024-10-31
    0人点赞
    Human IL-2 R alpha / CD25 Protein, His Tag
    在研究IL-2与其受体之间相互作用的项目中用到该抗原重组蛋白，ELISA结果显示，两者的结合亲和力很不错。流式细胞活性实验也已逐步开展中，期待细胞水平的结合数据也依然喜人。
  • ga*******126.com 2024-05-20
    0人点赞
    Human IL-2 R alpha / CD25 Protein, His Tag
    使用Human IL-2 R alpha蛋白主要用于优选突变抗体的筛选和验证，蛋白活性高，筛选结果及ELISA验证数据都很棒。百普塞斯蛋白销售老师服务态度也很赞。
  • 18********qq.com 2024-03-26
    0人点赞
    Human IL-2 R alpha / CD25 Protein, His Tag
    还是之前抗体筛选项目买的该抗原重组蛋白，本次用于相关多肽ELISA亲和力检测，蛋白保存很久了，但活性依然很稳定，质量真心不错，售后服务也很到位，值得推荐。
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  • 分子信息
  • 产品列表