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NCAM-1

NCAM-1信息

英文名称:Neural cell adhesion molecule 1上市药物数量0
中文名称神经细胞粘附分子-1临床药物数量5
靶点别称Neural cell adhesion molecule 1,CD56,NCAM1,NCAM,Neural Cell Adhesion Molecule, NCAM,CD56 Antigen,N-CAM-1,MSK39,NCAM-1,Antigen Recognized By Monoclonal Antibody 5.1H11最高研发阶段Phase 2 Clinical
英文名称:Neural cell adhesion molecule 1
中文名称神经细胞粘附分子-1
靶点别称Neural cell adhesion molecule 1,CD56,NCAM1,NCAM,Neural Cell Adhesion Molecule, NCAM,CD56 Antigen,N-CAM-1,MSK39,NCAM-1,Antigen Recognized By Monoclonal Antibody 5.1H11
上市药物数量0
临床药物数量5
最高研发阶段Phase 2 Clinical

NCAM-1产品列表

  • 属性

    Protein (7)

  • 产品库

    在线 (7)

  • 物种

    Human (6)Mouse (1)

  • 标签

    His Tag (3)Fc Tag (2)His Tag & Avi Tag (1)Llama IgG Fc Tag (1)

  • 标记

    Unconjugated (4)Biotin-labeled (1)FITC Labeled (2)

共 7 项数据
  • 1

NCAM-1分子背景

NCAM1 belongs to the immunoglobulin superfamily of adhesion molecules. A wide range of alternatively spliced NCAM1 messenger RNAs (mRNAs) has been described to date, but only the 120-, 140-, and 180- kDa isoforms are commonly expressed. NCAM1 plays an important role in the regulation of neurogenesis, neurite outgrowth, proliferation, and cell migration, however, its function in hematopoiesis, including NK cells, is poorly understood. NCAM1 signaling is mediated either by homophilic or heterophilic interactions with fibroblast growth factor receptor (FGFR), L1-CAM, N-cadherin and other components of the extracellular matrix. Upon activation, NCAM1 triggers a variety of signaling cascades including FYN–focal adhesion kinase (FAK), MAPK, and phosphatidylinositol 3-kinase (PI3K) pathways.

NCAM-1分子别名

CD56,MSK39,NCAM1,N-CAM-1

产品评论

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    0人点赞
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  • 13********qq.com 2022-12-09
    1人点赞
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  • ch********bardxera-bio.com 2022-10-27
    0人点赞
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  • 分子信息
  • 产品列表