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NOTCH3

NOTCH3信息

英文名称:Neurogenic locus notch homolog protein 3上市药物数量0
中文名称神经源性基因座notch同源蛋白-3临床药物数量0
靶点别称Neurogenic Locus Notch Homolog Protein 3，LMNS，Notch 3，NOTCH3，Notch (Drosophila) Homolog 3，Notch Homolog 3 (Drosophila)，Notch Homolog 3，CADASIL1，CADASIL，CASIL，IMF2，Receptor， Notch3，Notch Receptor 3最高研发阶段Preclinical
英文名称:Neurogenic locus notch homolog protein 3
中文名称神经源性基因座notch同源蛋白-3
靶点别称Neurogenic Locus Notch Homolog Protein 3，LMNS，Notch 3，NOTCH3，Notch (Drosophila) Homolog 3，Notch Homolog 3 (Drosophila)，Notch Homolog 3，CADASIL1，CADASIL，CASIL，IMF2，Receptor， Notch3，Notch Receptor 3
上市药物数量0
临床药物数量0
最高研发阶段Preclinical

NOTCH3产品列表

  • 属性

    Protein (1)

  • 产品库

    在线 (1)

  • 物种

    Human (1)

  • 标签

    Fc Tag (1)

  • 标记

    Unconjugated (1)

共 1 项数据
  • 1

NOTCH3分子背景

Notch3 is one of four mammalian Notch proteins, which act as signalling receptors and involve in developmental patterning, cell fate decisions, regulation of cell survival and proliferation. Notch3 could interact with membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Via ligand activation, notch intracellular domain (NICD) is released and forms a transcriptional activator RBPJ/RBPSUH complex, which activates genes of the enhancer of split locus. Consequently, the activation of Notch3 can lead to the implementation of differentiation, proliferation and apoptotic programs

NOTCH3分子别名

Notch-3,NOTCH3
  • 分子信息
  • 产品列表