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TNF-beta

TNF-beta信息

英文名称:Tumor necrosis factor β上市药物数量16
中文名称肿瘤坏死因子β临床药物数量4
靶点别称TNF Superfamily Member 1，TNLG1E，LT，Lymphotoxin-alpha，TNFSF1，Tumor Necrosis Factor Ligand Superfamily Member 1，Tumor Necrosis Factor Beta，LT-alpha，LTA#TNFB，LTA，Lymphotoxin Alpha，TNF-Beta，TNFB，Lymphotoxin Alpha (TNF Superfamily， Member 1)，Tumor Necrosis Factor Ligand 1E，Truncated Lymphotoxin Alpha，TNF Superfamily， Member 1最高研发阶段Approved
英文名称:Tumor necrosis factor β
中文名称肿瘤坏死因子β
靶点别称TNF Superfamily Member 1，TNLG1E，LT，Lymphotoxin-alpha，TNFSF1，Tumor Necrosis Factor Ligand Superfamily Member 1，Tumor Necrosis Factor Beta，LT-alpha，LTA#TNFB，LTA，Lymphotoxin Alpha，TNF-Beta，TNFB，Lymphotoxin Alpha (TNF Superfamily， Member 1)，Tumor Necrosis Factor Ligand 1E，Truncated Lymphotoxin Alpha，TNF Superfamily， Member 1
上市药物数量16
临床药物数量4
最高研发阶段Approved

TNF-beta产品列表

  • 属性

    Protein (2)

  • 产品库

    在线 (2)

  • 物种

    Human (2)

  • 标签

    His Tag (1)Fc Tag (1)

  • 标记

    Unconjugated (2)

共 2 项数据
  • 1

TNF-beta分子背景

TNF-beta is also known as Lymphotoxin-alpha (LT-alpha or LTA), Tumor necrosis factor ligand superfamily member 1 (TNFSF1), which belongs to the tumor necrosis factor family. TNF-beta can form homotrimer with itself or form heterotrimer of either two LTB and one LTA subunits or (less prevalent) two LTA and one LTB subunits. The homotrimer of TNF-beta is secreted and the heterotrimer is membrane-associated. The homotrimeric form of NF-beta binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR.

TNF-beta分子别名

LTA,DAMA-25N12,13-004,LT,TNFB,TNFSF1,LT-alpha,TNF-beta
  • 分子信息
  • 产品列表