选择语言
免费注册积分兑换
关注公众号
我的购物车
收藏产品

Polyclonal Olig2 Antibody, Rabbit IgG

COAMS
DS
用户评价
货号-规格
价格
Qty.
合计0件 产品金额0
0
加入购物车
新品建议
增项建议

产品详情

  • 抗体来源（Source）

    Polyclonal Olig2 Antibody, Rabbit IgG is a polyclonal antibody purified from rabbit serum.
    Gene Synonyms: Oligo2, bHLHe19, oligodendrocyte transcription factor 2.

  • 种属（Species）

    Rabbit polyclonal antibodies

  • 亚型（Isotype）

    Rabbit IgG

  • 抗体类型（Antibody Type）

    Polyclonal Antibody

  • 免疫原（Immunogen）

    Mouse Olig2 peptide fused to GST.

  • 特异性（Specificity）

    Usually, it is easier to get a positive signal in sections of juvenile animals than that of adults. This antibody does not recognize Olig1 and Olig3.

  • 应用（Application）

    Application
    Recommended Usage
    IF
    1:200

  • 纯化（Purification）

    Protein A purified / Protein G purified

  • 制剂（Formulation）

    Supplied as 0.2 μm filtered solution in PBS, 50 mM Glycine, 50 mM Tris with 40% glycerol as protectant.

    Contact us for customized product form or formulation.

  • 运输（Shipping）

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • 存储（Storage）

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. Shipped at -20°C. Store at -20°C for 20 months;
    2. Shipped at -20°C. Store at -70°C for 3 years.

  • 质量管理控制体系（QMS）

    1. 质量管理体系（ISO, GMP）
    2. 质量优势
    3. 质控流程

产品展示

  • 活性（Bioactivity）-Immunostaining

    Olig2 IMMUNOSTAINING

    2D cell staining: Immunofluorescent staining (10X) of cerebral organoid-derived neurons (CIPO-BWL001K) labeling Olig2 (Red) with purified OL2-S456 at 1:200 dilution. DAPI (blue) was used as nuclear counterstain.

    Protocol

  • Olig2 IMMUNOSTAINING

    3D organoid staining: Immunofluorescent staining (4x or 10X) of cerebral organoid-(CIPO-BWL001K) labeling Olig2 (Green) with purified OL2-S456 at 1:200 dilution. DAPI (blue) was used as nuclear counterstain. TUJ1 (red) is a neural differentiation marker commonly used to label neural processes.

    Protocol

用户评价
发表评论

背景介绍

The oligodendrocyte transcription factor 2 (Olig2) is a basic helix-loop-helix transcription factor which is highly expressed in the oligodendrocyte-lineage cells and in oligodendroglial tumors of the brain as well. Olig2 is an essential regulator of ventral neuroectodermal progenitor cell fate, especially regulating key stages of early oligodendrocyte development. Olig2 has also been reported to act as a gene repressor to determine the cell fate of motor neurons in the spinal cord. Olig2 is a useful marker for primary and mature oligodendrocytes as well as a marker of malignant glioma.

Zhang K, et al. Nat Commun. 2022;13(1):1423. doi: 10.1038/s41467-022-29068-z.

Ono K, et al. Mol Cells. 2009;27(4):397-401. doi: 10.1007/s10059-009-0067-2.

General Notes: FOR RESEARCH USE ONLY.

前沿进展

 
联系我们
项目合作
查看更多项目
  • 产品SKU
  • 产品详情
  • 产品展示
  • 用户评价
  • 背景介绍