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Human CD37 Protein, His Tag

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CD7-H52H3-100ug
¥3675.00
CD7-H52H3-1mg
¥24255.00
合计0件 产品金额¥ 0

产品详情

  • 分子别名(Synonym)

    CD37,Tspan-26,TSPAN26

  • 表达区间及表达系统(Source)

    Human CD37, His Tag (CD7-H52H3) is expressed from human 293 cells (HEK293). It contains AA Arg 112 - Asn 241 (Accession # P11049-1).

    Predicted N-terminus: Gly

    Request for sequence
  • 蛋白结构(Molecular Characterization)

    CD37 Structure

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 16.9 kDa. The protein migrates as 20-30 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • 偶联(Conjugate)

    Unconjugated

  • 内毒素(Endotoxin)

    Less than 1.0 EU per μg by the LAL method.

  • 纯度(Purity)

    90% as determined by SDS-PAGE.

  • 制剂(Formulation)

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 重构方法(Reconstitution)

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • 存储(Storage)

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

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  • 电泳(SDS-PAGE)

    CD37 SDS-PAGE

    Human CD37, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.

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背景介绍

Leukocyte antigen CD37 (CD37) is also known as Tetraspanin-26 (Tspan-26) and TSPAN26,which is a member of the transmembrane 4 superfamily or tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins encoded by CD37 gene mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD37 is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. CD37 may play a role in T-cell-B-cell interactions.

前沿进展

 
药物研发进展
  • 英文全称:

    Leukocyte antigen CD37

  • 中文全称:

    白细胞抗原CD37

  • 种类:

  • 上市药物数量:

    0 详情

  • 临床药物数量:

    5 详情

  • 最高研发阶段:

    临床二期

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