Human CD3 epsilon&CD3 delta Heterodimer Protein, Fc Tag&Fc Tag (MALS verified)

分子别名（Synonym）

CD3E & CD3D,CD3 delta & CD3 epsilon

表达区间及表达系统（Source）

Human CD3E&CD3D Heterodimer Protein, Fc Tag&Fc Tag (CDD-H5255) is expressed from human 293 cells (HEK293). It contains AA Asp 23 - Asp 126 (CD3E) & Phe 22 - Ala 105 (CD3D) (Accession # P07766-1 (CD3E) & P04234-1 (CD3D)).

Predicted N-terminus: Asp 23 (CD3E) & Phe 22 (CD3D)

蛋白结构（Molecular Characterization）

Human CD3E&CD3D Heterodimer Protein, Fc Tag&Fc Tag is produced by co-expression of CD3E and CD3D, has a calculated MW of 38.3 kDa (CD3E) and 35.8 kDa (CD3D). Subunit CD3E is fused with a human IgG1 Fc tag at the C-terminus and subunit CD3D is fused with a human IgG1 Fc tag at the C-terminus. As a result of glycosylation, the protein migrates as 45-60 kDa under reducing (R) condition, and 90-110 kDa under non-reducing (NR) condition (SDS-PAGE).

偶联（Conjugate）

Unconjugated

内毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

纯度（Purity）

90% as determined by SDS-PAGE.

90% as determined by SEC-MALS.

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

1. -20°C to -70°C for 12 months in lyophilized state;
2. -70°C for 3 months under sterile conditions after reconstitution.

质量管理控制体系（QMS）

1. 质量管理体系（ISO, GMP）
2. 质量优势
3. 质控流程