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Biotinylated Human CD7 Protein, Fc,Avitag™ (MALS verified)

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CD7-H82F3-25ug
¥3675.00
CD7-H82F3-200ug
¥14490.00
合计0件 产品金额¥ 0

产品详情

  • 分子别名(Synonym)

    CD7,GP40,TP41,LEU-9,Tp40

  • 表达区间及表达系统(Source)

    Biotinylated Human CD7, Fc,Avitag (CD7-H82F3) is expressed from human 293 cells (HEK293). It contains AA Ala 26 - Pro 180 (Accession # P09564-1).

    Predicted N-terminus: Ala 26

    Request for sequence
  • 蛋白结构(Molecular Characterization)

    CD7 Structure

    This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™).

    The protein has a calculated MW of 44.6 kDa. The protein migrates as 55-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • 偶联(Conjugate)

    Biotin

  • 标记(Labeling)

    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.

  • 内毒素(Endotoxin)

    Less than 1.0 EU per μg by the LAL method.

  • 纯度(Purity)

    95% as determined by SDS-PAGE.

    90% as determined by SEC-MALS.

  • 制剂(Formulation)

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 重构方法(Reconstitution)

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • 存储(Storage)

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

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  • 电泳(SDS-PAGE)

    CD7 SDS-PAGE

    Biotinylated Human CD7, Fc,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

  • SEC-MALS

    CD7 SEC-MALS

    The purity of Biotinylated Human CD7, Fc,Avitag (Cat. No. CD7-H82F3) is more than 90% and the molecular weight of this protein is around 95-115 kDa verified by SEC-MALS.

    Report
  • 活性(Bioactivity)-ELISA

     CD7 ELISA

    Immobilized Biotinylated Human CD7, Fc,Avitag (Cat. No. CD7-H82F3) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate can bind Anti-CD7 antibody, Mouse IgG1 with a linear range of 0.2-2 ng/mL (QC tested).

    Protocol

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背景介绍

T-cell antigen CD7 (CD7) is also known as GP40, LEU-9, TP41 and Tp40. CD7 is a protein that in humans is encoded by the CD7 gene, this gene encodes a transmembrane protein which is a member of the immunoglobulin superfamily. CD7 has been shown to interact with PIK3R1. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development.

前沿进展

 
药物研发进展
  • 英文全称:

    T-cell antigen CD7

  • 中文全称:

    T细胞抗原CD7

  • 种类:

  • 上市药物数量:

    0 详情

  • 临床药物数量:

    23 详情

  • 最高研发阶段:

    临床三期

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