My Cart

Biotinylated Anti-Human CD28 Antibody, Mouse IgG1,Avitag™, premium grade

Customer Reviews
Cat. No. / Size
Price
Qty
CD8-BM225-50ug
$100.00
CD8-BM225-500ug
$310.00
ETA of in-stock products:2 business days
Sub-Total$ 0

Product Details

  • Source

    Biotinylated Anti-Human CD28 Antibody, Mouse IgG1,Avitag, premium grade (CD8-BM225) is recombinantly produced from human 293 cells (HEK293).

    It is produced under our rigorous quality control system that incorporates a comprehensive set of tests including sterility and endotoxin tests. Product performance is carefully validated and tested for compatibility for cell culture use or any other applications in the early preclinical stage. When ready to transition into later clinical phases, we also offer a custom GMP protein service that tailors to your needs. We will work with you to customize and develop a GMP-grade product in accordance with your requests that also meets the requirements for raw and ancillary materials use in cell manufacturing of cell-based therapies.

  • Isotype

    Mouse IgG1 | Mouse Kappa

  • Conjugate

    Biotin

  • Specificity

    This product is a specific antibody specifically reacts with CD28.

  • Endotoxin

    Less than 0.002 EU per μg by the LAL method / rFC method.

  • Purity

    >95% as determined by SDS-PAGE.

    >95% as determined by SEC-MALS.

  • Sterility

    Negative

  • Mycoplasma

    Negative

  • Formulation

    Supplied as 0.2 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Shipping

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • Storage

    For long term storage, the product should be stored at liquid state at -70°C.

    This product is stable after storage at:

    1. 2-8°C for 12 months under sterile conditions;
    2. -70°C for 24 months.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

Customers Also Viewed

Performance Data

  • SDS-PAGE

    CD28 SDS-PAGE

    Biotinylated Anti-Human CD28 Antibody, Mouse IgG1,Avitag, premium grade on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

  • SEC-MALS

    CD28 SEC-MALS

    The purity of Biotinylated Anti-Human CD28 Antibody, Mouse IgG1,Avitag, premium grade (Cat. No. CD8-BM225) is more than 95% and the molecular weight of this protein is around 135-165 kDa verified by SEC-MALS.

    Report
  • Bioactivity-ELISA

     CD28 ELISA

    Immobilized Biotinylated Anti-Human CD28 Antibody, Mouse IgG1,Avitag, premium grade (Cat. No. CD8-BM225) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate can bind Human / Cynomolgus / Rhesus macaque CD28, His Tag with a linear range of 0.2-1 ng/mL (QC tested).

    Protocol

Customer Reviews
Writing Reviews

Background

T-cell-specific surface glycoprotein CD28 is also known as TP44, is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. is one of the molecules expressed on T cells that provide co-stimulatory signals, which are required for T cell activation. CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2). When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells.

Recent Advances

 
Drug Development Progress
  • English Name:

    T-cell-specific surface glycoprotein CD28

  • Category:

  • Approved Drugs:

    0 Details

  • Drugs in Clinical Trials:

    31 Details

  • Highest Development Stage:

    Phase 2 Clinical

Contact Us
Drug Candidate Licensing
More
  • Basic Product Information
  • Product Details
  • Customers Also Viewed
  • Performance Data
  • Customer Reviews
  • Background
Contact Us

[North America]: +1 800-810-0816
[Switzerland]: +41 800 040 012
[Asia & Pacific]: +86 400-682-2521

[North America]: 1 Innovation Way, Newark, DE 19711, USA
[Switzerland]: ACRObiosystems AG, c/o Zug Dammstrasse Centre AG, Dammstrasse 19, 6300 Zug Switzerland