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Product Details
Product Overview
Claudin18.2 participates in the proliferation, differentiation and migration of tumor cells. Recent studies have identified Claudin18.2 expression as a potential specific marker for the diagnosis and treatment of these tumors. The Claudin18.2 IHC Antibody (3B10) is a ready-to-use antibody working solution to detect Claudin18.2 across tumors to identify patients eligible for multiple targeted therapies. Kit product are manufactured in a dedicated GMP facility and are compliant with our ISO 13485 quality management system.
Product Specifications
AnalyteClaudin-18.2Format7.5mlReactivityHumanSpeciesMouseRegulatory StatusRUOApplicable PlatformLEICA BOND III、DAKO link 48Materials Provided
Recombinant Monoclonal Anti-Claudin18.2 Antibody, Mouse (3B10)
Application
The kit is developed for use in the Claudin18.2 protein in the formalin-fixed, paraffin-embedded tissue. It is indicated as an aid in the assessment of Claudin18.2 expression in human tissues.
State
Liquid
Storage
Stored at 2°C to 8°C. The shelf life is 30 days from the date of opening.
ACRO Quality Management System
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Performance Data
Consistency
LEICA BOND III and Dako link 48 platform conformance verification, with a high consistency rate (>95%).
Use ACRO Claudin18.2 3B10 to stain gastric cancer. The results showed that the staining effect was highly consistent.
Extensibility
ACRO Claudin18.2 3B10 expandable test: gastric cancer, pancreatic cancer, colorectal cancer and ovarian Cancer.
Use ACRO Claudin18.2 3B10 kit to stain gastric cancer, pancreatic cancer, colorectal cancer and ovarian cancer tissue samples respectively.
Applicability
ACRO Claudin18.2 3B10 kit can be available on the LEICA BOND III platform.
Use ACRO Claudin18.2 3B10 kit to stain NSCLC tissue samples at Leica BOND-III.
Control Sample
Use ACRO Claudin18.2 3B10 kit to stain normal gastric tissue and lung tissue, according to the cross-reactivity experiment, there is no cross-reactive staining result between Claudin-18.2 and Claudin-18.1.
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Recent Advances
Drug Development Progress- English Name：
Claudin-18 splice variant 2
- Category：
- Approved Drugs：
1 Details
- Drugs in Clinical Trials：
82 Details
- Highest Development Stage：
Approved
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