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B7-1 [Biotinylated] : CTLA-4 Inhibitor Screening ELISA Kit

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Cat. No. / Size
Price
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EP-116-96tests
$770.00
ETA of in-stock products:2 business days
Sub-Total$ 0

Product Details

  • Materials Provided

    ID
    Components
    Size
    EP116-C01
    High-bind Plate
    1 plate
    EP116-C02
    Human CTLA-4
    10 μg
    EP116-C03
    Biotinylated Human B7-1
    10 μg
    EP116-C04
    Anti-CTLA4 Neutralizing Antibody
    20 μg
    EP116-C05
    Streptavidin-HRP
    10 μg
    EP116-C06
    Coating Buffer
    12 mL
    EP116-C07
    10xWashing Buffer
    50 mL
    EP116-C08
    Blocking Buffer
    50 mL
    EP116-C09
    Substrate Solution
    12 mL
    EP116-C10
    Stop Solution
    7 mL

  • Product Overview

    B7-1 [Biotinylated] : CTLA-4 Inhibitor Screening ELISA Kit is based on a competition-ELISA method, is used to screening for inhibitors of human B7-1 binding to human CTLA-4. The kit is designed to provide a reliable solution for the screening of antibodies and small molecule inhibitors in the early stages, as well as QC release, to help researchers quickly screen and validate drugs, effectively improving research and development efficiency. It can also be used as a universal detection tool to identify the ability of human B7-1 binding to human CTLA-4.

  • Reconstitution

    Please see Certificate of Analysis for details of reconstitution instruction and specific concentration.

  • Storage

    1. Unopened kit should be stored at 2℃-8℃ upon receiving.

    2. Find the expiration date on the outside packaging and do not use reagents past their expiration date.

    3. The opened kit should be stored per components table. The shelf life is 30 days from the date of opening.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • Typical Data 

    Please refer to DS document for the assay protocol.

     CTLA-4 TYPICAL DATA

    INHIBITION OF B7-1 [BIOTINYLATED]: CTLA-4 BINDING BY ANTI-CTLA-4 NEUTRALIZING ANTIBODY
    Serial dilutions of Anti-CTLA-4 Neutralizing antibody (Catalog # EP116-C04) (1:1 serial dilution, from 10 μg/mL to 0.078μg/mL) was added into CTLA-4: Biotinlated B7-1 binding reactions. The assay was performed according to the protocol described below. Background was subtracted from data points prior to log transformation and curve fitting (QC tested).

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Drug Development Progress
  • English Name:

    Cytotoxic T-Lymphocyte-Associated Antigen 4

  • Category:

  • Approved Drugs:

    5 Details

  • Drugs in Clinical Trials:

    65 Details

  • Highest Development Stage:

    Approved

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