My Cart

Biotinylated Cynomolgus / Rhesus macaque BCMA / TNFRSF17 Protein, His,Avitag™ (MALS verified)

Customer Reviews
Cat. No. / Size
Price
Qty
BCA-C82E5-25ug
$470.00
BCA-C82E5-200ug
$2035.00
ETA of in-stock products:2 business days
Sub-Total$ 0

Product Details

  • Synonym

    TNFRSF17, CD269, BCM, BCMA

  • Source

    Biotinylated Cynomolgus / Rhesus macaque BCMA, His,Avitag (BCA-C82E5) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 53 (Accession # A0A2K5UD97-1). In the region Met 1 - Ala 53, the AA sequence of Cynomolgus and Rhesus macaque BCMA are homologus.

    Predicted N-terminus: Met 1

    Request for sequence

  • Molecular Characterization

    BCMA Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).

    The protein has a calculated MW of 9.6 kDa. The protein migrates as 15-18 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Labeling

    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.

  • Protein Ratio

    Passed as determined by the HABA assay / binding ELISA.

  • Purity

    >90% as determined by SDS-PAGE.

    >95% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

Customers Also Viewed

Performance Data

  • SDS-PAGE

    BCMA SDS-PAGE

    Biotinylated Cynomolgus / Rhesus macaque BCMA, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.

  • SEC-MALS

    BCMA SEC-MALS

    The purity of Biotinylated Cynomolgus / Rhesus macaque BCMA, His,Avitag (Cat. No. BCA-C82E5) is more than 95% and the molecular weight of this protein is around 12-17 kDa verified by SEC-MALS.

    Report
  • Bioactivity-ELISA

     BCMA ELISA

    Immobilized Human APRIL, His,Flag Tag, active trimer (Cat. No. APL-H52D1) at 2 μg/mL (100 μL/well) can bind Biotinylated Cynomolgus / Rhesus macaque BCMA, His,Avitag (Cat. No. BCA-C82E5) with a linear range of 0.2-1 ng/mL (QC tested).

    Protocol
  •  BCMA ELISA

    Immobilized Biotinylated Cynomolgus / Rhesus macaque BCMA, His,Avitag (Cat. No. BCA-C82E5) at 1 μg/mL (100 μL/well) on streptavidin precoated (0.5 μg/well) plate, can bind Human BAFF, Fc Tag, active trimer (Cat. No. BAF-H5261) with a linear range of 0.2-5 ng/mL (Routinely tested).

    Protocol

Customer Reviews
Writing Reviews

Background

Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.

Recent Advances

 
Drug Development Progress
  • English Name:

    B-cell maturation protein

  • Category:

  • Approved Drugs:

    8 Details

  • Drugs in Clinical Trials:

    145 Details

  • Highest Development Stage:

    Approved

Contact Us
Drug Candidate Licensing
More
  • Basic Product Information
  • Product Details
  • Customers Also Viewed
  • Performance Data
  • Customer Reviews
  • Background
Contact Us

[North America]: +1 800-810-0816
[Switzerland]: +41 800 040 012
[Asia & Pacific]: +86 400-682-2521

[North America]: 1 Innovation Way, Newark, DE 19711, USA
[Switzerland]: ACRObiosystems AG, c/o Zug Dammstrasse Centre AG, Dammstrasse 19, 6300 Zug Switzerland