Product Details
Synonym
DLEC, CLEC4C, BDCA-2, CD303, CLECSF11, CLECSF7, HECL
Source
Cynomolgus CLEC4C Protein, Fc Tag (CLC-C5253) is expressed from human 293 cells (HEK293). It contains AA Tyr 48 - Ile 212 (Accession # A0A2K5UWP4-1).
Predicted N-terminus: Pro
Request for sequenceMolecular Characterization

Other Tags and Version Biotin & Other Labeled Version
This protein carries a human IgG1 Fc tag at the N-terminus.
The protein has a calculated MW of 45.9 kDa. The protein migrates as 53-63 KDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity
>90% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.
Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Storage
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
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Performance Data
SDS-PAGE

Cynomolgus CLEC4C Protein, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).
SEC-MALS

The purity of Cynomolgus CLEC4C Protein, Fc Tag (Cat. No. CLC-C5253) is more than 90% and the molecular weight of this protein is around 95-120 kDa verified by SEC-MALS.
Report
Bioactivity-ELISA

Immobilized Cynomolgus CLEC4C Protein, Fc Tag (Cat. No. CLC-C5253) at 0.5 μg/mL (100 μL/well) can bind Litifilimab with a linear range of 0.1-2 ng/mL (QC tested).
Protocol
Customer Reviews Writing Reviews

Background
Recent Advances
- English Name:
C-Type lectin domain family 4 member C
- Category:
- Approved Drugs:
0 Details
- Drugs in Clinical Trials:
9 Details
- Highest Development Stage:
Phase 3 Clinical
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