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Human DLL3 (353-492) Protein, His Tag

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货号-规格
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Qty.
DL3-H52Ha-100ug
¥3675.00
DL3-H52Ha-1mg
¥24255.00
合计0件 产品金额¥ 0

产品详情

  • 分子别名(Synonym)

    Delta3,delta-like 3 (Drosophila),delta-like protein 3,DLL3,Pudgy,SCDO1,SCDO1delta3

  • 表达区间及表达系统(Source)

    Human DLL3 (353-492) , His Tag (DL3-H52Ha) is expressed from human 293 cells (HEK293). It contains AA Arg 353 - Leu 492 (Accession # Q9NYJ7-1).

    Predicted N-terminus: Arg 353

    Request for sequence
  • 蛋白结构(Molecular Characterization)

    DLL3 Structure

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 16.4 kDa. The protein migrates as 18 kDa and 19-21 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • 偶联(Conjugate)

    Unconjugated

  • 内毒素(Endotoxin)

    Less than 1.0 EU per μg by the LAL method.

  • 纯度(Purity)

    90% as determined by SDS-PAGE.

  • 制剂(Formulation)

    Supplied as 0.2 μm filtered solution in PBS, pH7.4.

    Contact us for customized product form or formulation.

  • 运输(Shipping)

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • 存储(Storage)

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.
  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

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  • 电泳(SDS-PAGE)

    DLL3 SDS-PAGE

    Human DLL3 (353-492) , His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.

  • 活性(Bioactivity)-ELISA

     DLL3 ELISA

    Immobilized Human DLL3 (353-492) , His Tag (Cat. No. DL3-H52Ha) at 1 μg/mL (100 μL/well) can bind Anti-DLL3 Antibody (specific Binding EGFs of DLL3), Human IgG1 with a linear range of 0.1-2 ng/mL (QC tested).

    Protocol

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背景介绍

Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands.May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. DLL3 protein is expressed on the surface of tumor cells but not in normal adult tissues.

前沿进展

 
药物研发进展
  • 英文全称:

    Delta-like protein 3

  • 中文全称:

    δ样蛋白-3

  • 种类:

  • 上市药物数量:

    1 详情

  • 临床药物数量:

    17 详情

  • 最高研发阶段:

    批准上市

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