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BCMA

BCMA信息

英文名称:B-cell maturation protein上市药物数量7
中文名称B细胞成熟蛋白临床药物数量120
靶点别称B-Cell Maturation Protein,B-Cell Maturation Factor,B Cell Maturation Antigen,CD269 Antigen,Tumor Necrosis Factor Receptor Superfamily Member 17,TNFRSF17,TNFRSF13A,CD269,BCM,BCMA,TNF Receptor Superfamily Member 17,Tumor Necrosis Factor Receptor Superfamily, Member 17,B-Cell Maturation Antigen最高研发阶段临床三期
英文名称:B-cell maturation protein
中文名称B细胞成熟蛋白
靶点别称B-Cell Maturation Protein,B-Cell Maturation Factor,B Cell Maturation Antigen,CD269 Antigen,Tumor Necrosis Factor Receptor Superfamily Member 17,TNFRSF17,TNFRSF13A,CD269,BCM,BCMA,TNF Receptor Superfamily Member 17,Tumor Necrosis Factor Receptor Superfamily, Member 17,B-Cell Maturation Antigen
上市药物数量7
临床药物数量120
最高研发阶段Phase 3 Clinical

BCMA产品列表

  • 属性

    Protein (27)Antibody (1)Beads (1)Cell Grade Beads (1)Kits (1)Cell (1)

  • 产品库

    在线 (34)

  • 物种

    Human (20)Cynomolgus / Rhesus macaque (5)Mouse (4)Canine (1)Rabbit (1)Rat (1)

  • 标签

    Fc Tag (4)His Tag (15)Fc Tag & Avi Tag (3)Llama IgG Fc Tag (2)His Tag & Avi Tag (3)Mouse IgG Fc Tag (1)Mouse IgG1 (1)- (5)

  • 标记

    Unconjugated (13)FITC Labeled (3)Biotin-labeled (6) (3)PE Labeled (2)APC Labeled (2)AF488 Labeled (1)AF647 Labeled (1)AF555 Labeled (1)

共 32 项数据
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BCMA分子背景

Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.

BCMA分子别名

TNFRSF17,CD269,BCM,BCMA

抗体项目交易平台

Licensing 项目合作

产品评论

  • ch*******genscriptprobio.com 2025-03-23
    0人点赞
    用了ACRO家的biotinlated human BCMA 抗原,进行了亲和力成熟抗体筛选,通过ELISA和SPR,筛选到了亲和力相比parental WT提升100倍的突变克隆。抗原性质稳定,批次间没有差异,助力项目获得非常好的分子。
  • ch*******genscriptprobio.com 2025-03-23
    0人点赞
    用了ACRO家的mouse,cyno,human BCMA 抗原,进行了抗体工程改造和亲和力成熟抗体筛选,通过ELISA和SPR,筛选到了亲和力相比parental WT提升100倍以上的克隆,同时满足亲和力提升和不同种属交叉。抗原性质稳定。
  • ch*******genscriptprobio.com 2025-03-23
    0人点赞
    用了ACRO家的cynomolgus BCMA 抗原,进行了抗体工程改造和亲和力成熟抗体筛选,通过ELISA和SPR,筛选到了亲和力相比parental WT提升500倍的克隆,筛选到了多个亲和力提升100倍且不同种属交叉的分子。
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