选择语言

Cynomolgus NKp46 / NCR1 / CD335 Protein, His Tag (MALS verified)

用户评价
货号-规格
价格
Qty.
NC1-C52H4-100ug
¥3675.00
NC1-C52H4-1mg
¥24255.00
合计0件 产品金额¥ 0

产品详情

  • 分子别名(Synonym)

    NCR1,LY94,CD335,NK-p46,hNKp46

  • 表达区间及表达系统(Source)

    Cynomolgus NKp46, His Tag (NC1-C52H4) is expressed from human 293 cells (HEK293). It contains AA Pro 22 - Arg 257 (Accession # Q95JB9-1).

    Predicted N-terminus: Pro 22

    Request for sequence
  • 蛋白结构(Molecular Characterization)

    NKp46 Structure

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 28.6 kDa. The protein migrates as 34-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • 偶联(Conjugate)

    Unconjugated

  • 内毒素(Endotoxin)

    Less than 1.0 EU per μg by the LAL method.

  • 纯度(Purity)

    90% as determined by SDS-PAGE.

  • 制剂(Formulation)

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 重构方法(Reconstitution)

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • 存储(Storage)

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

产品展示

  • 电泳(SDS-PAGE)

    NKp46 SDS-PAGE

    Cynomolgus NKp46, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.

  • SEC-MALS

    NKp46 SEC-MALS

    The purity of Cynomolgus NKp46, His Tag (Cat. No. NC1-C52H4) is more than 85% and the molecular weight of this protein is around 28-42 kDa verified by SEC-MALS.

    Report
  • 活性(Bioactivity)-ELISA

     NKp46 ELISA

    Immobilized Cynomolgus NKp46, His Tag (Cat. No. NC1-C52H4) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-NKp46 Antibody, Human IgG1 with a linear range of 0.1-1 ng/mL (QC tested).

    Protocol

用户评价
发表评论

背景介绍

Natural cytotoxicity triggering receptor 1 (NCR1) is also known as Natural killer cell p46-related protein (NK-p46), Lymphocyte antigen 94 homolog (LY94), CD antigen CD335, which belongs to the natural cytotoxicity receptor (NCR) family. NCR1 contains two Ig-like (immunoglobulin-like) domains. NCR1 interacts with CD247 and FCER1G. NCR1 / CD335 may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.

前沿进展

 
药物研发进展
  • 英文全称:

    Natural cytotoxicity triggering receptor 1

  • 中文全称:

  • 种类:

  • 上市药物数量:

    0 详情

  • 临床药物数量:

    4 详情

  • 最高研发阶段:

    临床二期

联系我们
项目合作
查看更多项目
  • 产品SKU
  • 产品详情
  • 产品展示
  • 用户评价
  • 背景介绍