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Biotinylated Mouse PSCA Protein, His,Avitag™, low endotoxin (MALS verified)

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货号-规格
价格
Qty.
PSA-M82Ea-100ug
¥7245.00
PSA-M82Ea-1mg
¥91875.00
PSA-M82Ea-5mg
¥306600.00
合计0件 产品金额¥ 0

产品详情

  • 分子别名(Synonym)

    PSCA,UNQ206,PRO232

  • 表达区间及表达系统(Source)

    Biotinylated Mouse PSCA, His,Avitag (PSA-M82Ea) is expressed from human 293 cells (HEK293). It contains AA Leu 21 - Asn 95 (Accession # P57096-1).

    Predicted N-terminus: Leu 21

    Request for sequence
  • 蛋白结构(Molecular Characterization)

    PSCA Structure

    This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).

    The protein has a calculated MW of 12.0 kDa.

  • 偶联(Conjugate)

    Biotin

  • 标记(Labeling)

    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.

  • 内毒素(Endotoxin)

    Less than 0.01 EU per μg by the LAL method.

  • 纯度(Purity)

    95% as determined by SEC-MALS.

  • 制剂(Formulation)

    Supplied as 0.2 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 运输(Shipping)

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • 存储(Storage)

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

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  • SEC-MALS

    PSCA SEC-MALS

    The purity of Biotinylated Mouse PSCA, His,Avitag (Cat. No. PSA-M82Ea) is more than 95% and the molecular weight of this protein is around 18-26 kDa verified by SEC-MALS.

    Report

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背景介绍

The Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored protein, plays an important role in tumorigenesis. The prostate stem cell antigen (PSCA) gene, which encodes a prostate-specific antigen (PSA), was identified as a gene involved in cell adhesion and proliferation. PSCA may be involved in the regulation of cell proliferation. Has a cell-proliferation inhibition activity in vitro. May act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits nicotine-induced signaling probably implicating alpha-3:beta-2- or alpha-7-containing nAChRs.

前沿进展

 
药物研发进展
  • 英文全称:

    Prostate stem cell antigen

  • 中文全称:

    前列腺干细胞抗原

  • 种类:

  • 上市药物数量:

    0 详情

  • 临床药物数量:

    3 详情

  • 最高研发阶段:

    临床一期

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